CONFERENCE DAY ONE | WEDNESDAY, FEBRUARY 5, 2025

8:15 am Check In & Morning Coffee

8:55 am Chair’s Opening Remarks

Exploring Novel Technologies to Enhance Gene Editing Capabilities

9:00 am Harnessing the power of targeted meiotic recombination for crop improvement

Synopsis

  • Create genetic diversity in low recombination regions in the genome.
  • Removal of linkage drag to isolate and enhance traits like disease resistance from wild varieties.
  • Development of complex traits—such as flavor and drought tolerance by integrating multiple genetic elements for resilient and productive crops

9:30 am Unlocking Agricultural Potential with CRISPR: Innovations & Advancements in AgBio

  • Aaron Hummel Vice President - Technology & Pipeline Strategy, Pairwise

Synopsis

  • Exploring how CRISPR is transforming agriculture by unlocking new possibilities for crop enhancement and genetic innovation
  • Presenting successful CRISPR-driven products, such as Pairwise’s leafy greens and blackberry innovations, demonstrating the tangible impact of gene-editing technology
  • Demonstrating how partnerships between small biotech firms and larger industry players amplify innovation and help capture broader opportunities in the AgBio space

10:00 am Unlocking Traits with Native Gene Expression Control

Synopsis

  • Harnessing CRE.AI.TIVE™ an AI-driven platform to identify precise genetic changes that yield impactful and resilient plant traits, drastically reducing the time and cost of conventional breeding processes
  • Beyond AI, implementing footprint-free genome editing to rapidly introduce traits into crops, achieving scalable improvements across diverse plant species without transgenes
  • Driving precision-bred products to market through collaboration to achieve sustainable agriculture, enhance crop resilience, and enable future food systems

10:30 am Morning Break & Speed Networking

Synopsis

Join us for an exciting speed networking session. This fast-paced, high-energy format encourages quick, focused conversations, giving you the opportunity to make meaningful connections with peers, industry experts, and potential collaborators. Break the ice quickly in a structured setting, allowing you to skip the usual networking awkwardness and dive right into meaningful conversations.

Developing Next-Generation Delivery Systems to Overcome Technical Barriers

11:30 am Innovating Gene Editing: Overcoming Delivery Challenges with EDGE™ Technology

Synopsis

  • Learning how “Edge” technology addresses the common need for plant regeneration during transformation, improving efficiency in gene editing processes
  • Exploring the key features of the “Edge” system and its role in advancing CRISPR applications for crops like tomatoes, melons, and cucumbers
  • Understanding how BetterSeeds integrates delivery technology into broader product development strategies, accelerating commercialization of edited plant varieties

12:00 pm Precision Genome Engineering for Commercial Crops: Enhancing CRISPR Efficiency and Transformation

  • Piero Barone Capability Leader, Genome Editing, Corteva Agriscience

Synopsis

  • Streamlining high-throughput genome engineering pipelines using advanced plant tissue culture and transformation techniques (biolistic and Agrobacterium) for efficient trait development in commercial crops
  • Optimizing CRISPR gene editing tools to improve efficiency, specificity, and application across different crops, addressing challenges like disease resistance and climate adaptability
  • Refining gene delivery, selection, and regeneration protocols through proprietary technologies and innovative problem-solving to push the boundaries of traditional plant breeding and transformation methods

Improving Trait & Crop Selection to Meet Market & Environmental Demands

12:30 pm Harnessing Cell-Penetrating Peptides for Enhanced Protein Delivery in Plant Biotechnology

  • Markita Landry Associate Professor, University of California, Berkeley

Synopsis

  • Highlight the benefits of using CPPs over traditional delivery methods (e.g. Agrobacterium, biolistics)
  • Explore potential future applications of CPP technology in enhancing crop traits, such as disease resistance and stress tolerance
  • Discuss the integration of CPPs into existing plant transformation protocols and their role in advancing sustainable agriculture practices

Lunch

2:00 pm Advancing Non-Transgenic Trait Development in Specialty Crops

  • Shai Lawit Director - Trait Strategy & Testing, Pairwise

Synopsis

  • Overcoming the challenge of transforming plants without inserting transgenes to preserve existing commercial traits in vegetatively propagated crops
  • Addressing the unique difficulties of working with orphan or underdeveloped crops like black raspberries, requiring complete sequencing and transformation technology development
  • Leveraging insights from successful transformations in crops like blackberries to accelerate trait development in other crops, such as cherries

2:30 pm Domestication of a New Cover Crop: Enhancing Trait Selection for Climate- Resilient Agriculture

Synopsis

  • Strategies for selecting traits that support off-season growth and adaptability to changing climate conditions
  • Integrating CRISPR and advanced gene-editing tools to accelerate crop domestication
  • Aligning trait development with market demands for sustainability and environmental resilience

3:00 pm Improving Food System Sustainability Using Seedesign

  • Jamie Saxon Senior Director, External Innovation and Sustainability, Inari

Synopsis

  • Leveraging the natural diversity of seed to develop crops that improve the sustainability of food production
  • Identifying novel editing targets using AI-powered predictive design
  • Utilizing comprehensive multiplex editing toolbox to make changes to the genome and affect plant phenotype

3.30 pm Afternoon Break & Poster Session

4:00 pm Increasing Yield by Editing Crops for Climate Resilience to Increase Survival & Productivity

  • Tal Sherman Chief Innovation & Technology Officer, BetterSeeds

Synopsis

  • Developing gene-edited crops that thrive in changing climates by focusing on traits that improve a plant’s ability to withstand stressors such as heat and drought
  • Targeting drought and soil salinity resistance to boost yield through precise genetic modifications that enhance crops’ survival and productivity
  • Providing examples of increased crop productivity through gene editing to illustrate how these innovations have already led to improved yields

Enhancing Collaboration & Investment Strategies to Accelerate Innovation in Gene-Editing for AgBio

4:30 pm Fireside Chat: Fostering Collaboration to Drive Innovation in AgBio

Synopsis

  • Building successful partnerships between industry, academia, and government by fostering collaboration that leverages expertise from all sectors to accelerate innovation and product development
  • Leveraging joint expertise to speed up product development by combining scientific research, regulatory knowledge, and market insights to bring gene-edited products to market faster and more efficiently
  • Sharing examples of effective collaboration leading to breakthrough innovations to highlight how multi-sector partnerships have driven the successful development and commercialization of gene-edited crops

5:15 pm Securing Investments for the Future of Gene Editing

  • Balaji Vasudevan Venture Partner & Agrifoodtech Consultant, 16 VC & UM6P Ventures

Synopsis

  • Understanding the investment landscape for AgBio and gene-editing technologies by exploring current funding trends and opportunities for gene-editing startups and emerging technologies
  • Implementing strategies for securing funding for new gene-edited products by identifying key investor interests and aligning projects with market trends to attract financial backing
  • Identifying key trends shaping the future of gene-editing startups and innovations by examining emerging technologies and investment opportunities that will define the next decade of agricultural biotech

5:45 pm Chair’s Closing Remarks